The Downtown Eastside is a neighbourhood in Vancouver, British Columbia, Canada. One of the city's oldest neighbourhoods, the DTES is the site of a complex set of social issues, including disproportionately high levels of drug use, homelessness, poverty, crime, mental illness and sex work. It is also known for its strong community resilience, history of s…The Downtown Eastside is a neighbourhood in Vancouver, British Columbia, Canada. One of the city's oldest neighbourhoods, the DTES is the site of a complex set of social issues, including disproportionately high levels of drug use, homelessness, poverty, crime, mental illness and sex work. It is also known for its strong community resilience, history of social activism, and artistic contributions.