Preparations are underway as an arctic blast dives into the nation's interior and southern regions and pushes a snowstorm into the Mid-Atlantic and Northeast that will be followed by lethal cold.

Extreme cold could expose residents of several states to conditions like hypothermia and frostbite over the weekend.

Even the Mississippi Coast will take a hit. Biloxi is expected to experience several nights with lows at or below freezing. That may not sound very impressive compared to Oxford's predicted 13 degrees, but down on the Coast, that's chilly, y'all.

Temperatures will plummet by up to 40 degrees this weekend as an arctic blast spreads across much of the U.S., including the Deep South.

Grand Junction is expected to hit temperatures as low as 5 degrees Fahrenheit and Montrose is believed to hit 0 degrees. These temperatures, as explained by forecaster Dalen Brazelton, are coming from the north.

An arctic blast will send temperatures across the United States plummeting as bitterly cold air that originated in Siberia will arrive from Canada by week’s end, bringing with it dangerously cold wind chills for millions of Americans.

A potent shot of Arctic air starts settling in Monday as a massive dip in the jet stream pulls in frigid air across the entire eastern half of the country. Temperatures are set to drop as low as 20 degrees below average Tuesday and Wednesday with highs only reaching the teens,