For all the observations on the changes in prostate tissues affected by estrogens as well as the associated risk of cancer, relatively little is known about the exact mechanisms by which these ...
A new study shows how prostate cancer cells use valine and isoleucine metabolism to sustain cholesterol synthesis under ...
Prostate cancer begins as an androgen-dependent tumor that undergoes clinical regression in response to pharmacological or surgical strategies that reduce testosterone concentration. Despite this ...
Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL ...
Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may ...
A study led by Cancer Center at Illinois (CCIL) member Jason Ridlon, associate professor of animal sciences in the College of Agricultural, Consumer and Environmental Sciences (ACES), has revealed ...
CaP: Prostate cancer; DPN: Diarylpropionitrile; E: Estradiol 17b; ER: Estrogen receptor; GPR: G-protein-coupled receptor; MPP: Methyl-piperidino-pyrazole; PC ...