A review in Glycoscience & Therapy summarizes advances in selective editing of N-glycan signals on living cell surface via the LCS‑NGS technology platform. It focuses on enzyme‑based strategies ...

Living cell surface N-glycans act as a "glycan code" that mediates cell–cell communication, immune recognition, and disease progression. Unlike ...

A collaborative research group, including researchers from Nagoya City University, National Institutes of Natural Sciences, and RIKEN has uncovered a molecular tool, the "passport sequence," that ...

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function. These ...

Researchers at National Taiwan University have developed a tip-enhanced Raman spectroscopy platform that can identify tiny structural differences in oligosaccharides without fluorescent labels. The ...

When researchers at the National Institute of Standards and Technology (NIST) need a special tool to do their work more effectively, they often prove that necessity is truly the mother of invention.

Microscopic droplets fluoresce bright blue with specks of green. Five droplets in this image (two at the top, two near the center, and one near the bottom) fluoresce blue in varying brightness; each ...

For decades, dermatologists have been researching the genetic cause of aging skin so that the perfect antidote could be developed. When examining genes and proteins, a difference between younger and ...

Sepsis—an extreme inflammatory response in the bloodstream caused by a serious infection—could be responsible for as many as 11 million deaths worldwide per year, according to a 2020 report from the ...

They observed that N-glycan processing of the spike protein's S1 subunit is comparable between the virus and the vaccine candidate. However, they observed O-linked glycosylation at the T678 site on ...