Researchers at the Josep Carreras Leukaemia Research Institute propose a new view of cancer based on spatial hallmark ecosystems and its evolution during cancer progression. This conceptual framework ...

Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel hallmarks that help tumors grow, spread, and resist treatment. Now a new wave of ...

An enduring challenge for the study of human cancer is just how complex it is: how many different ways there are for cancers to originate, progress, and spread in the people who are diagnosed with ...