The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

Smooth muscle differentiation is induced in the embryonic bladder by the centrally located urothelium in the undifferentiated mesenchyme in the periphery adjacent to the serosa. We hypothesize that ...

A research team reports that muscle-invasive bladder cancer (MIBC) is dangerous not only because tumor cells breach the bladder’s detrusor muscle, but also because that invasion can reprogram the ...