Fruitfly biologists have developed some elaborate genetic tricks to express transgenes in a spatially restricted manner. The bipartite GAL4/UAS system exploits the yeast GAL4 transcriptional activator ...
Researchers have observed a male bias in protein expression in primordial germ cells, which develop into the cells that pass on genetic material during reproduction, of the fruit fly, Drosophila. When ...
The binary Gal4–UAS system has been used to drive the tissue-specific expression of transgenes in a number of animal models. In the February 5 issue of Proceedings of the National Academy of Sciences, ...