Christian McCaffrey is one of the most exciting players on the San Francisco 49ers roster. The 28-year-old star, who was ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

"Nobody knows" when Christian McCaffrey will be ready to return from injured reserve, 49ers coach Kyle Shanahan said Sunday.

Ask teammates about McCaffrey and many will compare his "gravity" to that of Golden State Warriors guard Stephen Curry. The ...

San Francisco 49ers running back Christian McCaffrey has been placed on injured reserve due to Achilles tendinitis, which ...

Alvin Kamara surpassed Christian McCaffrey in career touchdowns scored, ranking sixth-best among active players. Klint Kubiak ...

Justin Jefferson, who hauled in a wild 97-yard touchdown catch in the first half, left the game early with a quad injury.

San Francisco 49ers star running back Christian McCaffrey could be out for six weeks or more due to his calf soreness and ...

The 49ers are partly to blame for why Christian McCaffrey will be out at least four games and possibly more as he nurses ...

The reigning NFC champions faced a puzzling loss on Sunday. The San Francisco 49ers lost to the Minnesota Vikings 23-17 as ...

Jordan Mason has been great so far for the 49ers this season, but if he were to suffer an injury before McCaffrey returns, ...

49ers coach Kyle Shanahan said the timeline for running back Christian McCaffrey’s return is unknown.