In the recent article, “Antisense Oligonucleotide Therapy for Calmodulinopathy,” we provided the first proof-of-concept in ...

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Such findings were generally ignored because multiple epidemiological studies have demonstrated reduced cardiovascular disease (CVD) events with increasing levels of physical activity (PA). Randomized ...

The recent study by Bortolin et al, 1 “Antisense Oligonucleotide Therapy for Calmodulinopathy,” presents an innovative therapeutic strategy for rare inherited arrhythmia syndromes. By leveraging ...

Elevated plasma levels of Lp(a) [lipoprotein(a)] are a causal risk factor for coronary heart disease and stroke in European individuals, but the causal relevance of Lp(a) for different stroke types ...

Clinical effectiveness of catheter ablation in atrial fibrillation (AF) is typically characterized by 12-month freedom from atrial tachyarrhythmia recurrence. However, freedom from AF burden may serve ...

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Background: There is sparse high-quality safety and effectiveness data for pulsed field ablation (PFA) of persistent atrial fibrillation (PerAF), where lesions beyond pulmonary vein isolation (PVI) ...

Arteriovenous malformations (AVMs) and intracranial aneurysms contribute to a high degree of morbidity and mortality due to the risk of intracranial hemorrhage observed in each of these ...

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Despite major advances in recent years, the timely detection and prevention of incipient congestion in patients with chronic heart failure remains challenging. Most approaches are either invasive or ...