Background: Mitochondrial dysfunction is linked to myocardial ischemia-reperfusion (I/R) injury. Checkpoint kinase 1 (CHK1) could facilitate cardiomyocyte proliferation and cardiac repair post ...
The antioxidant effect of the ACE inhibitor captopril has also been evaluated in a rat ischemia-reperfusion model. Both captopril and prazosin decreased lipid peroxidation in this model ...
Several observations from preclinical and short-term clinical studies support a role for sildenafil in the treatment of heart failure patients. The following discussion briefly considers each of ...
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