1). There are two major apoptotic pathways known to date, initiated by either the mitochondria (the 'intrinsic' pathway) or the cell surface receptors (the 'extrinsic' pathway). Mitochondria ...

Department of Anesthesiology, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China Myocardial ischemia-reperfusion injury (MIRI) is a secondary injury caused by restoring blood ...

In humans, the main molecular energy carrier is adenosine triphosphate (ATP). It is critical for cellular functions all over ...

(Mainichi/Koichiro Tezuka) OSAKA -- Ischemic heart disease accounts for about 5% of deaths in Japan, including that of famous actor Toshiyuki Nishida, who passed away on Oct. 17 at 76. The ...

Pontine strokes happen when the blood supply to the pons region of the brainstem is cut off. They can be ischemic strokes, which occur when a blood clot blocks flow, or hemorrhagic strokes, which ...

is an innovative strategy for the treatment of mitochondrial dysfunction such as cardiac ischemic reperfusion injuries, traumatic brain and spinal cord injuries, cerebral stroke, and neurodegenerative ...

Arrhythmias are a major public health burden and a major cause of morbidity and mortality (Srinivasan and Schilling, 2018). Pharmacologic anti-arrhythmic agents targeting ion channel activity have ...

7A). Mouse aorta mitochondria were damaged by acrolein, resulting in decreased MMP and JC-1 dye uptake. The effect of Pue on mitochondrial function in mouse aortas induced by acrolein was ...

reducing ischemia-reperfusion (IR) injury. GJA1-20k localizes to the outer membrane of mitochondria, stabilizes actin, and mediates an actin mediated mitochondrial protection. The mechanism is not ...

Myocardial infarction (MI), which caused 110,000 deaths in America in 2020, occurs following a complete blockage (ischemia ... of the mitochondrial permeability transition pore (mPTP) is the major ...