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Ana Elisa Gonçalves, PhD | Além da Farmacologia on Instagram: "COX-1 ou COX-2: por que a seletividade dos AINEs importa tanto? Os AINEs atuam inibindo a enzima ciclooxigenase (COX), mas nem todos fazem isso do mesmo jeito! A COX-1 é constitutiva, ou seja, está sempre presente no organismo, protegendo a mucosa gástrica, regulando a função plaquetária e o fluxo renal. Já a COX-2, além de participar de processos homeostáticos, também é induzida no processo inflamatório, sendo a principal responsáve
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